Gene interactions and pathways from curated databases and text-mining

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HES5 — SELP

Text-mined interactions from Literome

Chen et al., Acta Anaesthesiol Scand 2006 : HES200/0.5 and HES130/0.4 reduced the CD42b, CD41/61 and CD62p expression of ADP-agonist activated platelets at 15 min after intravenous infusion
Handrigan et al., Shock 2005 : The effect of HES on endothelial cell surface expression of E-selectin, P-selectin , vascular cell adhesion molecule-1 ( VCAM-1 ), and intracellular adhesion molecule-1 ( ICAM-1 ) was evaluated by enzyme linked immunoabsorbant assay ... After stimulation with IL-1 ( 10 U/mL ), HES had no effect on the expression of P-selectin , E-selectin, ICAM-1, or VCAM-1
Sossdorf et al., Crit Care 2009 (Inflammation) : At 40 % but not at 10 % haemodilution rate, HES 200/0.5 also increased platelet fibrinogen binding and both HES solutions increased expression of CD62P , the main receptor for platelet-leukocyte adhesion