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FOS — SETD2
Text-mined interactions from Literome
Yamashita et al., J Biol Chem 2001
:
The results support essential
roles for
AP-1 , GATA-2, and NF-1 in stabilizing the binding of
HIF-1 and promoting recruitment of p300/CBP to the ET-1 hypoxia response complex
Nanduri et al., Respir Physiol Neurobiol 2008
(Anoxia) :
Compared to same duration and intensity of CH, IH is more potent in activating HIF-1 and c-fos and also results in long lasting accumulation of HIF-1alpha and c-fos mRNA, a phenomenon that was not seen with CH. IH-evoked transcriptional activation by HIF-1, c-fos as well as the resulting
activator protein-1 (AP-1) requires reactive oxygen species ( ROS ) -mediated signaling and
involves complex feed forward interactions between
HIF-1 and ROS