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HDAC1 — SLAMF1
Text-mined interactions from Literome
Howie et al., Blood 2002
:
Molecular dissection of the signaling and costimulatory functions of CD150 ( SLAM ) :
CD150/SAP binding and
CD150 mediated
costimulation
Li et al., J Biol Chem 2003
(Lymphoproliferative Disorders) :
Because SAP also blocked the recruitment of SHP-2 to SLAM in these cells, we propose a dual functional
role for
SAP in
SLAM signaling by acting both as an adaptor for FynT and an inhibitor to SHP-2 binding
Simarro et al., Int Immunol 2004
:
SAP increases FynT kinase activity and is
required for phosphorylation of
SLAM and Ly9 ... Here we demonstrate that
SAP is
required for phosphorylation of both
SLAM and Ly9 in thymocytes and peripheral T cells
Chen et al., Mol Cell Biol 2006
:
SAP promotes
SLAM family receptor induced protein tyrosine phosphorylation, due to its capacity to recruit the Src related kinase FynT
McCausland et al., J Immunol 2007
:
SAP regulation of follicular helper CD4 T cell development and humoral immunity is
independent of
SLAM and Fyn kinase
Yusuf et al., J Immunol 2010
:
These data illustrate complexities of
SAP dependent
SLAM family receptor signaling, revealing a prominent role for SLAM receptor ligation in IL-4 production by GC CD4 T cells but not in T ( FH ) cell and GC T ( FH ) cell differentiation