Gene interactions and pathways from curated databases and text-mining

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CASP1 — SLCO6A1

Text-mined interactions from Literome

Tashiro et al., Anticancer Drugs 2001 (Hepatoblastoma...) : Additionally, the expression of GST-pi in HepG2 cells caused a decrease in GSH-DXR induced activation of caspase-3 , which was an apoptotic marker, whereas the suppression of GST-pi in HT29 cells showed an increase in caspase-3 activation
Asakura et al., Int J Cancer 2001 (Liver Neoplasms, Experimental) : A conjugate of doxorubicin and glutathione via glutaraldehyde ( GSH-DXR ) inhibited glutathione S-transferase (GST) activity of rat hepatoma AH66 cells, and treatment of the cells with GSH-DXR induced caspase-3 activation and DNA fragmentation
Seitz et al., J Clin Immunol 2003 (MAP Kinase Signaling System) : However, GST selectively inhibited the activity of the interleukin-1 converting enzyme (ICE)/caspase-1 ... However, GST selectively inhibited the activity of the interleukin-1 converting enzyme (ICE)/caspase-1