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AKT3 — SOAT1
Text-mined interactions from Literome
Song et al., Chin J Cancer 2002
(Multiple Myeloma) :
IL-6 inhibited apoptosis of XG-7 cells through up-regulation of Mcl-1 and the
activation of
JAK/STAT rather than Ras/MAPK nor
PI-3K/Akt signal transduction pathway
Amaravadi et al., J Clin Invest 2005
(Inflammation...) :
The PI3K dependent activation of the
Akt kinases and the
JAK/STAT dependent
induction of the Pim kinases are examples of partially overlapping survival kinase pathways
Sharma et al., Endocr Relat Cancer 2006
(Endometrial Neoplasms...) :
Moreover, leptin induced phosphorylation of ERK2 and
AKT was
dependent on
JAK/STAT activation
Saxena et al., Cancer Res 2007
(Carcinoma, Hepatocellular...) :
Leptin induced phosphorylation of ERK and
AKT was
dependent on Janus activated kinase ( JAK )
/STAT activation
Quaglino et al., BMC cell biology 2009
:
In addition, we found that mammary cell stretching triggered involution associated cellular events as Leukemia Inhibitory Factor (LIF) expression induction,
STAT3 activation and
AKT phosphorylation
inhibition
Dedoni et al., J Neurochem 2010
(Neuroblastoma) :
Similarly, in mouse primary neurons IFN-ß induced
STAT phosphorylation, caspase 3 cleavage and
inhibition of
Akt signaling
Min et al., J Pineal Res 2012
:
Inhibitory effects of melatonin on the lipopolysaccharide induced CC chemokine expression in BV2 murine microglial cells are mediated by suppression of
Akt induced NF-?B and
STAT/GAS activity