Abidi et al., Int J Mol Med 2005
(MAP Kinase Signaling System) :
Collectively, these new findings establish an important role of ERK signaling pathway in SCAP ligand induced transcription of LDLR and imply that the protein synthesis or turnover rate of SREBP-2 may be regulated by ERK Arito et al., J Biol Chem 2008
(MAP Kinase Signaling System) :
An ERK cascade inhibitor, U0126, inversely augmented SUMO modification of SREBP-2