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NFKB1 — STAT5A

Pathways - manually collected, often from reviews:

• FastForward regulation: NFKB1 → STAT5A (transcriptional regulation, unknown) Schreiber et al., Proc Natl Acad Sci U S A 2006
  Evidence: DNABINDING

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: STAT5A — NFKB1 (physical association, affinity chromatography technology) Della Chiara et al., J Mol Biol 2011*

Text-mined interactions from Literome

Nakamura et al., J Biol Chem 2002 (MAP Kinase Signaling System) : Analyzing the effects of several inhibitors or mutant receptors revealed that this NF-kappa B activation is mediated neither by MEK/ERK/MAPK nor by the phosphatidylinositol 3-kinase pathway but by STAT5 ... In addition, STAT5 dependent NF-kappa B activation is mediated not through an inducible nuclear translocation but via up-regulation of both DNA binding activity and transactivation potential of NF-kappa B
Hinz et al., J Exp Med 2002 (Hodgkin Disease) : Intriguingly, NF-kappaB positively regulates STAT5a expression and signaling pathways in HRS cells, and promotes its persistent activation
Giron-Michel et al., Blood 2003 : Differential STAT3, STAT5 , and NF-kappaB activation in human hematopoietic progenitors by endogenous interleukin-15 : implications in the expression of functional molecules
Nagy et al., Molecular cancer 2009 (Lymphoma) : Moreover, depletion of STAT5 via selective antisense oligonucleotide treatment similarly resulted in decreased BCL10 mRNA and protein expression, cellular viability and impaired NFkappaB activity independent of IL-2