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SYK — VEGFA

Text-mined interactions from Literome

Chakraborty et al., J Biol Chem 2006 (Anoxia...) : Moreover, Syk and Lck play differential roles in regulating Sp1 activation and expressions of melanoma cell adhesion molecule (MelCAM), urokinase-type plasminogen activator ( uPA ), matrix metalloproteinase-9 (MMP-9), and vascular endothelial growth factor ( VEGF ) in response to H/R. Overexpression of wild type Syk inhibited the H/R induced uPA, MMP-9, and VEGF expression but up-regulated MelCAM expression
Fruchon et al., Leukemia 2012 (Lymphoma, Follicular...) : Moreover, using Syk small interfering RNA and the Syk inhibitor R406, we demonstrate that, in FL cells, Syk is involved in the regulation of MMP-9 and VEGF expression, and that invasion and angiogenesis is mediated through a phosphatidylinositol-3 kinase (PI3K)-mammalian target of rapamycin module
Wang et al., J Pharmacol Exp Ther 2012 (Asthma) : Further investigation of potential regulatory mechanisms revealed that inhibition of Syk suppressed HRV induced vascular endothelial growth factor expression while promoting the activation of caspase-3, a mediator of epithelial cell apoptosis