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SRC — TCF4

Text-mined interactions from Literome

Gelain et al., Cell Signal 2006 : In this work, we report that, in Sertoli cells, retinol ( 7 microM ) induces the Src dependent activation of ERK1/2 MAPK and the ERK1/2 mediated phosphorylation of the transcription factor CREB
Chao et al., Oncogene 2007 (Gastrointestinal Neoplasms...) : Enhanced tumorigenicity of CCK ( 2i4sv ) R is associated with an Src dependent increase in the transcription factor , hypoxia-inducible factor-1alpha, its downstream target, vascular endothelial growth factor and tumor micro-vessel density, suggesting that CCK ( 2i4sv ) R may contribute to the growth and spread of GI cancers through agonist independent mechanisms that enhance tumor angiogenesis
Matteucci et al., Mol Cancer Res 2007 (Breast Neoplasms...) : Thus, the CXCR4 induction by HGF in MCF-7 cells required NF-kappaB and Ets1 activations, downstream of phosphoinositide-3-kinase/Akt, whereas in HGF treated MDA-MB231 cells, HDAC3 activation via c-Src probably caused a reduction of transcription factor activities, such as that of NF-kappaB
Walker et al., Philos Trans R Soc Lond B Biol Sci 2010 : Also, testosterone activation of Src , EGF receptor and ERK kinases as well as the activation of the CREB transcription factor and CREB mediated transcription is reviewed