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TEC — TNF
Text-mined interactions from Literome
Zemans et al., Cell Immunol 2009
:
Furthermore, LPS induced actin polymerization as well as MCP-1,
tumor necrosis factor-alpha , interleukin-6, and interleukin-1beta expression are
dependent on
Tec kinase activity
Schmidt et al., Eur J Immunol 2009
:
Finally, a comparison of WT, Tec ( - ) ( / ) ( - ), Btk ( - ) ( / ) ( - ) and Tec ( - ) ( / ) ( - ) Btk ( - ) ( / ) ( - ) BMMC revealed a negative role for Btk in the regulation of IL-4 production, while for the efficient production of
TNF-alpha , IL-13 and GM-CSF, both
Tec and Btk were
required
Schwarting et al., J Immunol 1998
(Autoimmune Diseases...) :
By comparison,
TNF-alpha induces apoptosis in MC, but not
TEC , of the MRL-Fas ( lpr ) strain