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TERF2IP — VEGFA
Text-mined interactions from Literome
Tawa et al., Circ Res 2010
(Disease Models, Animal...) :
These results demonstrate a novel molecular mechanism by which
Rap1 and afadin
regulate the
VEGF- and S1P induced angiogenesis
Lakshmikanthan et al., Blood 2011
:
Using ECs obtained from Rap1-deficient mice we demonstrate that
Rap1b promotes
VEGF-VEGFR2 kinase activation and regulates integrin activation ... Importantly, the
Rap1b dependent
VEGF-VEGFR2 activation is in part mediated via integrin a ( v ) ß ( 3 ) ... These results provide a novel insight into the
role of
Rap1 in
VEGF signaling in ECs
Li et al., J Huazhong Univ Sci Technolog Med Sci 2011
:
VEGF stimulated
Rap1 activity, phosphorylation of ERK and Akt, cyclin D1 expression and cell proliferation were repressed in HUVECs overexpressing Rap1GAP as compared to empty vector transfected control