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JAK2 — TLR2
Text-mined interactions from Literome
Li et al., Zhongguo Wei Zhong Bing Ji Jiu Yi Xue 2003
(Burns...) :
[ Potential
role of
JAK/STAT in regulating
Toll-like receptor 2 gene expression in rats with postburn Staphylococcus aureus sepsis ]
Walker et al., Arch Virol Suppl 2005
(Ehrlichiosis) :
Ehrlichiae attach to L-selectin and E-selectin,
inhibit phagolysosomal fusion, apoptosis, and
JAK/STAT activation, and downregulate IL-12, IL-15, IL-18,
TLR2 and 3, and CD14 ... Ehrlichiae attach to L-selectin and E-selectin,
inhibit phagolysosomal fusion, apoptosis, and
JAK/STAT activation, and downregulate IL-12, IL-15, IL-18,
TLR2 and 3, and CD14
Melkamu et al., Journal of cell communication and signaling 2013
:
TLR2 up-regulation by poly I:C was also
reduced by IL-6Ra-nAb and inhibitors of
Jak2 , Stat3 and NF-?B phosphorylation, whereas RANTES secretion was unaffected, but abolished following NF-?B inhibition