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TLR4 — VEGFA

Text-mined interactions from Literome

Botero et al., J Endod 2006 : TLR4 mediates LPS induced VEGF expression in odontoblasts ... These results demonstrate that odontoblast-like cells express CD14 and TLR4, and that LPS induced VEGF expression is mediated , at least in part, by TLR4 signaling
Rodríguez-Martínez et al., Exp Eye Res 2006 : LPS induced the expression of VEGF in a dose dependent manner, and the blocking of TLR4 with an anti-TLR4 antibody prevented VEGF expression
Cho et al., Immunol Lett 2007 (Arthritis, Rheumatoid) : Thus, TLR-2 activation in RA FLS by microbial constituents could be involved in the induction of VEGF and IL-8 and thereby promote inflammation either directly or via angiogenesis
Koff et al., Am J Physiol Lung Cell Mol Physiol 2008 : We conclude that multiple TLR ligands induce airway epithelial cell production of IL-8 and VEGF via a Duox1 -- > ROS -- > TACE -- > TGF-alpha -- > EGFR phosphorylation pathway
Pei et al., Cell Immunol 2008 (Prostatic Neoplasms) : We further elucidated that functionally activation of TLR4 is essential for the increased VEGF and TGFbeta(1) mRNA expression in the cells
Heo et al., Immunol Lett 2008 (Inflammation) : Moreover, NOS inhibitor ( L-NAME ) and anti-TLR 4mAb reduced the LPS induced NO, IL-8 and VEGF production and ICAM-1 expression
Sow et al., Dev Comp Immunol 2009 (Respiratory Distress Syndrome, Newborn...) : We report that VEGF induced the expression of chemokines ( IL-8, RANTES, MCP-1 ), cytokines ( IFN-gamma, IL-6, TNF-alpha, GMCSF ), Toll-like receptor (TLR)-4 , complement family members ( C3, CFB, CFH ) and collectins ( SP-A, SP-D )
Grinberg et al., Am J Pathol 2009 (Inflammation) : This switch involves induction of A ( 2A ) Rs by TLR agonists, down-regulation of tumor necrosis factor alpha (TNFalpha) and interleukin-12, and up-regulation of vascular endothelial growth factor ( VEGF ) and interleukin-10 expression
Spirig et al., PloS one 2010 : In addition, we could show that TLR stimulation resulted in an increase of HIF-1alpha controlled VEGF secretion
Paolillo et al., Int J Immunopathol Pharmacol 2012 : Induction of VEGF and MMP-9 expression by toll-like receptor 2/4 in human endothelial cells infected with Chlamydia pneumoniae