Gene interactions and pathways from curated databases and text-mining

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NFKB1 — UCN

Text-mined interactions from Literome

Yeow et al., Br J Cancer 2006 (Neoplasms) : The weak VA-mediated induction of apoptosis of thoracic cancer cells can be profoundly enhanced either by Parthenolide, a pharmacologic inhibitor of NF-kappaB , or by UCN-01 a kinase inhibitor that has already undergone phase I clinical development
Huang et al., J Mol Endocrinol 2009 : Urocortin induces interleukin-6 release from rat cardiomyocytes through p38 MAP kinase, ERK and NF-kappaB activation ... Ucn also activates nuclear factor kappa B (NF-kappaB) and a NF-kappaB inhibitor blocks Ucn induced IL-6 release ... Finally, the CRH-R antagonists alpha-helical ( 9-41 ) CRH and astressin-2B completely inhibit Ucn induced IL-6 release, as well as activation of ERK, p38, and NF-kappaB