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IL8 — UTP15

Text-mined interactions from Literome

Idzko et al., Br J Pharmacol 2003 : Release of IL-8 was triggered by UDP, ATP, alpha, beta-meATP and BzATP, but not by UTP or ADP
Marcet et al., J Cell Physiol 2007 : Furthermore, UTP had no effect on interleukin-(IL)-8 release and reduced the release of both CCL20 and IL-8 induced by TNF-alpha and LPS
Relvas et al., Invest Ophthalmol Vis Sci 2009 : This investigation focused on whether extracellular nucleotides could contribute to this activation, and the effects of ATPgammaS, UTP , and UDP on the production of IL-8 by RPE cells was studied in relation to their expression of functional P2Y receptors ... Stimulation of ARPE-19 cells with ATPgammaS, UTP , and UDP induced IL-8 gene transcription and protein secretion ... TNFalpha induction of IL-8 secretion was also increased by ATPgammaS, UTP , and UDP ... ATPgammaS, UTP , and UDP stimulate both basal and TNFalpha induced IL-8 secretion in RPE cells through an ERK 1/2 dependent pathway