Gene interactions and pathways from curated databases and text-mining

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EPHB2 — XAF1

Text-mined interactions from Literome

Ju et al., Biochem J 2013 (Breast Neoplasms...) : We found that activation of ERK resulted in a decrease in XAF1 [ XIAP ( X-linked inhibitor of apoptosis ) -associated factor 1 ] which reduced the formation of the XIAP-XAF1 E3 ligase complex to ubiquitinate survivin
Park et al., Int J Oncol 2013 : ROS and ERK1/2 mediated caspase-9 activation increases XAF1 expression in dexamethasone induced apoptosis of EBV transformed B cells