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IGF2 — IGFALS

Pathways - manually collected, often from reviews:

• Reactome Reaction: IGFALS → IGF2 (reaction) Janosi et al., J Biol Chem 1999*, Okabe et al., FEBS Lett 1999*, Gibson et al., Growth Horm IGF Res 1999, Twigg et al., Endocrinology 2000*, Belgorosky et al., Horm Res 1999*, Bond et al., J Endocrinol 2000, Angelloz-Nicoud et al., Growth Horm IGF Res 1998*, Galanis et al., J Endocrinol 2001*, Overgaard et al., J Biol Chem 2001, Firth et al., Endocrinology 2001*, Laursen et al., FEBS Lett 2001, Schneider et al., Biochem Biophys Res Commun 2001, Booth et al., Am J Physiol Endocrinol Metab 2002, Hoeflich et al., Cancer Res 2001, Baxter et al., J Clin Endocrinol Metab 2002, Mohan et al., J Endocrinol 2002, Firth et al., Endocr Rev 2002, Payet et al., Endocrinology 2003*, Baxter et al., J Biol Chem 1992*, Cohen et al., J Clin Endocrinol Metab 1992*, Payet et al., J Clin Endocrinol Metab 2004*, Choi et al., J Biochem Mol Biol 2004*, Yan et al., J Biol Chem 2004*, Holly et al., Neuroendocrinology 2006, Baxter et al., Proc Natl Acad Sci U S A 1989*, Arai et al., J Biol Chem 1994, Fowlkes et al., J Biol Chem 1994, Lee et al., J Clin Endocrinol Metab 1994*, Cohen et al., J Endocrinol 1994*, Lalou et al., Endocrinology 1994*, Fielder et al., Growth Regul 1994, Juul et al., J Clin Endocrinol Metab 1995, Angelloz-Nicoud et al., Endocrinology 1995*, Bach et al., J Biol Chem 1993, Cianfarani et al., Experientia 1993, Bach et al., Biochim Biophys Acta 1996, Rajah et al., Prog Growth Factor Res 1995, Angelloz-Nicoud et al., Growth Regul 1996*, Lalou et al., Horm Res 1996*, Twigg et al., J Biol Chem 1998*, Collett-Solberg et al., J Clin Endocrinol Metab 1998*, Twigg et al., J Biol Chem 1998*, Rajah et al., Am J Respir Cell Mol Biol 1999
• Reactome Reaction: IGFALS → IGF2 (direct_complex) Janosi et al., J Biol Chem 1999*, Twigg et al., Endocrinology 2000*, Belgorosky et al., Horm Res 1999*, Bond et al., J Endocrinol 2000, Galanis et al., J Endocrinol 2001*, Firth et al., Endocrinology 2001*, Baxter et al., J Clin Endocrinol Metab 2002, Mohan et al., J Endocrinol 2002, Firth et al., Endocr Rev 2002, Payet et al., Endocrinology 2003*, Baxter et al., J Biol Chem 1992*, Payet et al., J Clin Endocrinol Metab 2004*, Choi et al., J Biochem Mol Biol 2004*, Yan et al., J Biol Chem 2004*, Holly et al., Neuroendocrinology 2006, Baxter et al., Proc Natl Acad Sci U S A 1989*, Arai et al., J Biol Chem 1994, Juul et al., J Clin Endocrinol Metab 1995, Bach et al., J Biol Chem 1993, Cianfarani et al., Experientia 1993, Bach et al., Biochim Biophys Acta 1996, Twigg et al., J Biol Chem 1998*, Collett-Solberg et al., J Clin Endocrinol Metab 1998*, Twigg et al., J Biol Chem 1998*

Text-mined interactions from Literome

Mucci et al., Cancer Epidemiol Biomarkers Prev 2010 (Prostatic Neoplasms) : The acid-labile subunit (ALS) acts in the insulin-like growth ( IGF ) system by binding circulating IGF-I in a ternary complex with binding protein ( IGFBP)-3 to prevent IGF-I from crossing the endothelial barrier
Baxter et al., J Biol Chem 1989 : Pure ALS formed a complex with BP-53 ( Ka approximately 5 x 10 ( 8 ) M-1 ), immunoprecipitable by anti-BP-53 antiserum, only in the presence of IGF-I or IGF-II
Baxter et al., J Clin Endocrinol Metab 1995 (Fibroma...) : Compared with normal IGF-II, pro-IGF-II inhibited ALS binding to IGFBP-3 in vitro
Scharf et al., Hepatology 1996 : Insulin, IGF-I , and GH increased ALS expression
Frystyk et al., Endocrinology 1998 : We describe a novel competitive assay for rat insulin-like growth factor (IGF) binding protein-3 ( rIGFBP-3 ) based on the ability of IGFBP-3 to form a ternary complex with the acid labile subunit (ALS) in the presence of IGF