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BDNF — MAP2K5
Text-mined interactions from Literome
Cavanaugh et al., J Neurosci 2001
:
BDNF stimulation of ERK5
required the activity of
MEK5
Carrasco et al., Neuroscience 2007
(Synaptic Transmission) :
The effects of
BDNF were
mediated by receptor tyrosine kinase B (TrkB) and
mitogen activated protein kinase kinase ( MEK ) activation since culturing neurons with either ( 9S,10R,12R ) -2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-9,12-epoxy-1H-diindolo [ 1,2,3-fg : 3',2',1'- kl ] pyrrolo [ 3,4-i ] [ 1,6 ] benzodiazocine-10-carboxylic acid methyl ester ( K252a ) or 2- ( 2-amino-3-methoxyphenyl ) -4H-1-benzopyran-4-one ( PD98059 ) blocked the augmentation in synaptic activity induced by the neurotrophin