Gene interactions and pathways from curated databases and text-mining

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CAT — NOS3

Text-mined interactions from Literome

Drummond et al., Circ Res 2000 : Induction of eNOS by H ( 2 ) O ( 2 ) was not affected by the hydroxyl radical scavenger DMSO, mannitol, or N-tert-butyl-alpha-phenylnitrone, but it was inhibited by the antioxidants N-acetylcysteine, ebselen, and exogenously added catalase ... Unlike H ( 2 ) O ( 2 ), the 4.0-fold induction of eNOS by shear stress ( 15 dyne/cm ( 2 ) for 6 hours ) was not inhibited by N-acetylcysteine or exogenous catalase
Jang et al., Biochem Pharmacol 2004 : Catalase induces the expression of inducible nitric oxide synthase through activation of NF-kappaB and PI3K signaling pathway in Raw 264.7 cells
Dong et al., Diabetologia 2006 (Insulin Resistance) : Catalase ablated insulin-resistance induced mechanical dysfunction, ROS production and protein damage, and reduced eNOS , but not insulin insensitivity
Lorenz et al., Basic Res Cardiol 2009 : Whereas stimulation of eNOS activity by EGCG was only slightly affected by pretreatment of cells with various ROS scavengers, TF3 ( theaflavin-3',3-digallate ) -induced eNOS activity was partially inhibited by PEG-catalase
Kumar et al., Am J Physiol Lung Cell Mol Physiol 2010 : We also found that the overexpression of catalase significantly attenuated the shear mediated increases in H2O2, phospho-Ser1177 eNOS , and NO generation
Dao et al., J Cell Mol Med 2011 : These data suggest that physiological venous catalase activity prevents exercise induced up-regulation of eNOS and ecSOD
Rengasamy et al., Biochem Pharmacol 1994 : Effect of hydrogen peroxide and catalase on rat cerebellum nitric oxide synthase ... The effect of H2O2 and catalase on isolated rat cerebellum nitric oxide ( NO ) synthase activity was determined by measuring the conversion of L- [ 3H ] arginine to L- [ 3H ] citrulline
Rotzinger et al., Life Sci 1995 : The nitric oxide synthase inhibitor NW-nitro-L-arginine methylester attenuates brain catalase activity in vitro