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Son et al., Biochem Biophys Res Commun 2002
(MAP Kinase Signaling System) :
Moreover, soluble NCAM also induced a Ras dependent MAPK activation ... Conversely, MAPK activation led to an increase in the expressions of all three isoforms of NCAM ... Treatment of neurons with tPA and plasminogen induced a Ras dependent MAPK activation and tPA-plasmin degradation of NCAM was mediated in a MAPK dependent manner
Shin et al., Exp Mol Med 2002
:
Western blot analysis showed that NCAM increased the expression levels of CaMKII, p-MAPK , GluR1 and NR1 but decreased p-STAT3