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PTH — PTX3
Text-mined interactions from Literome
Kestenbaum et al., Kidney Int 2004
(Hyperparathyroidism, Secondary...) :
Parathyroidectomy (
PTX ) can dramatically
reduce parathyroid hormone (PTH) and phosphate levels ; however, the relationship between PTX and survival is not known
Vidal et al., Am J Physiol Heart Circ Physiol 2006
(Hyperaldosteronism) :
We found that 1 ) the hypercalciuria and hypermagnesuria and decline ( P < 0.05 ) in plasma [ Ca2+ ] o and [ Mg2+ ] o that occur with AldoST were not altered by the Ca2+ supplemented diet alone or with PTx ; 2 ) the rise ( P < 0.05 ) in plasma
PTH with AldoST, with or without the Ca2+ supplemented diet, was
prevented by
PTx; 3 ) increased ( P < 0.05 ) PBMC [ Ca2+ ] i and H2O2 production, increased total Ca2+ in heart and skeletal muscle, and fall in bone Ca2+ and Mg2+ and plasma alpha1-antiproteinase activity with AldoST were abrogated ( P < 0.05 ) by PTx ; and 4 ) gp91(phox) activation in right and left ventricles at 4 wk of AldoST was attenuated by PTx. AldoST is accompanied by SHPT, with parathyroid gland derived calcitropic hormones being responsible for Ca2+ overload in diverse tissues and induction of oxidative stress
Tamura et al., J Bone Miner Metab 2007
(Hyperparathyroidism) :
PTX also
resulted in significant decreases in
PTH , 1,25 ( OH ) ( 2 ) D, BAP, IOC, NTx, and DPD that continued for at least 3 years after PTX
Jung et al., J Hypertens 2012
(Aortic Diseases...) :
In subtotally nephrectomized rats, we studied to what extent high-dose calcitriol induced cardiovascular disease can be modulated by almost complete suppression of
parathyroid hormone (PTH) ,
mediated by either cinacalcet ( CINA ) or parathyroidectomy (
PTX )
De Schutter et al., Calcif Tissue Int 2012
(Hyperparathyroidism...) :
However, whereas excessive woven bone accompanied by a dramatically increased osteoid width/area was seen in the CRF + vitD group, CIN treatment and
PTX resulted in significantly reduced serum
PTH level, which was accompanied by a distinct reduction of both the bone formation rate and the amount of osteoid