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EPO — KITLG
Pathways - manually collected, often from reviews:
-
NCI Pathway Database Signaling events mediated by Stem cell factor receptor (c-Kit):
SCF/KIT/EPO/EPOR complex (EPO-EPOR-KITLG-KIT)
→
SCF/KIT complex (KITLG-KIT)
(modification, activates)
Weiler et al., Blood 1996
Evidence: assay
-
NCI Pathway Database Signaling events mediated by Stem cell factor receptor (c-Kit):
KIT (KIT)
→
SCF/KIT/EPO/EPOR complex (EPO-EPOR-KITLG-KIT)
(modification, collaborate)
Li et al., J Biol Chem 2003*
Evidence: assay
-
NCI Pathway Database Signaling events mediated by Stem cell factor receptor (c-Kit):
EPOR (EPOR)
→
SCF/KIT/EPO/EPOR complex (EPO-EPOR-KITLG-KIT)
(modification, collaborate)
Li et al., J Biol Chem 2003*
Evidence: assay
-
NCI Pathway Database Signaling events mediated by Stem cell factor receptor (c-Kit):
EPO (EPO)
→
SCF/KIT/EPO/EPOR complex (EPO-EPOR-KITLG-KIT)
(modification, collaborate)
Li et al., J Biol Chem 2003*
Evidence: assay
-
NCI Pathway Database Signaling events mediated by Stem cell factor receptor (c-Kit):
EPO (EPO)
→
SCF (KITLG)
(modification, collaborate)
Li et al., J Biol Chem 2003*
Evidence: assay
-
NCI Pathway Database Signaling events mediated by Stem cell factor receptor (c-Kit):
SCF/KIT/EPO/EPOR complex (EPO-EPOR-KITLG-KIT)
→
SCF (KITLG)
(modification, collaborate)
Li et al., J Biol Chem 2003*
Evidence: assay
Text-mined interactions from Literome
Fukuda et al., Biochem Biophys Res Commun 2002
:
CIP29 mRNA expression is cytokine regulated in hematopoietic cells, being
up-regulated by
Epo in UT7/Epo cells, and by thrombopoietin (Tpo), FLT3 ligand ( FL ) and
stem cell factor (SCF) in primary human CD34 ( + ) cells
Hayman et al., Cell 1993
:
Interestingly,
Epo induced differentiation in the SCF progenitors even when
SCF was present
Wakao et al., EMBO J 1995
:
Interleukin 2 and
erythropoietin activate
STAT5/MGF via distinct pathways