◀ Back to CDK1

CDK1 — SPDYA

Pathways - manually collected, often from reviews:

• KEGG Oocyte meiosis: Complex of CDK1-SPDYA-SPDYC → CDC25C (protein-protein, activation)
• KEGG Progesterone-mediated oocyte maturation: SPDYA/SPDYC → CDK1 (protein-protein, activation)

Text-mined interactions from Literome

Kume et al., Biol Reprod 2007 : Porcine SPDYA2 ( RINGO A2 ) stimulates CDC2 activity and accelerates meiotic maturation of porcine oocytes
Al Sorkhy et al., BMC cancer 2012 (Breast Neoplasms...) : Collectively, this work supports that Spy1 is a unique activator of Cdk1 in breast cancer cells and may represent a valuable drug target and/or a prognostic marker for subsets of breast cancers
Zhang et al., J Mol Neurosci 2012 (Brain Neoplasms...) : Altered expression of Spy1 led to changes in cell cycle processes, cyclin dependent kinase 2 activity, and p27kip1 protein stabilization, ultimately disrupting cell growth rate