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FCGR1A — IL10

Text-mined interactions from Literome

Beigier-Bompadre et al., Clin Diagn Lab Immunol 2001 : Considering the biological relevance of the regulation of FcgammaRI, we investigated the effect of FMLP on the overexpression of FcgammaRI induced by both IFN-gamma and IL-10 on human monocytes ... We demonstrate that FMLP significantly abrogated IFN-gamma- and IL-10 induced FcgammaRI expression, although its basal level of expression was not altered
van Roon et al., Arthritis Rheum 2003 (Arthritis, Rheumatoid) : Consistent with these effects on SF macrophages, CD64-RiA also inhibited TNFalpha production, interleukin-1beta production, and cartilage degrading activity of RA synovial tissue explants
Beigier-Bompadre et al., Clin Exp Immunol 2003 (Tuberculosis, Pulmonary) : Although the prototypic formyl peptide N-formyl-methionyl-leucyl-phenylalanine ( FMLP ) is a well-known proinflammatory agonist, we have demonstrated previously that preincubation of monocytes with FMLP inhibited the up-regulation of FcgammaRI induced by IFN-gamma or IL-10 ... In conclusion, in this study we demonstrated the existence of two novel mechanisms that may contribute to the pathological effects generated by M. tuberculosis : the enhancement of FcgammaRI in response to IFN-gamma and IL-10 , and the unresponsiveness to the anti-inflammatory effects induced by formyl peptides
te Velde et al., J Immunol 1992 : The IL-10 induced Fc gamma RI expression is specific because anti-IL-10 antibodies completely reverse the IL-10 induced surface expression of Fc gamma RI and correlate with an enhanced capacity to lyse anti-D coated human rhesus positive erythrocytes
Soldan et al., J Immunol 2003 (Multiple Sclerosis, Chronic Progressive...) : The increase in IL-5 was primarily due to an increase in CD4 ( + ) and CD8 ( + ) T cells, the increase in IL-10 was primarily due to an increase in CD64 ( + ) monocytes/macrophages with some effect in T cells, while the decrease in TNF-alpha was primarily due to a decrease in CD8 ( + ) T cells
Chu et al., J Immunol 2010 (Chronic Disease...) : We found that IgG1 and IgG2a/c induce IL-10 from macrophages in vitro equally well but through different Fc?R subtypes : IgG1 through Fc?RIII and IgG2a/c through Fc?RI primarily, but also through Fc?RIII
Frausto-Del-Río et al., Cytokine 2012 (Calcium Signaling) : Thus, Fc?Rs mediated phagocytosis in monocyte derived macrophages ( MDM ) increases after IL-10 treatment, and decreases after treatment with IFN?, although both IL-10 and IFN? up regulate Fc?RI expression
Fujii et al., Journal of signal transduction 2013 : These findings suggest that IVIG induced the upregulation of IL-10 production through Fc?RI activation, and IL-10 was indispensable to the suppressing effect of IVIG on the production of IL-12p70 in LPS stimulated BMDC
de Waal Malefyt et al., J Immunol 1993 : IL-13 induced up-regulation of class II MHC Ag and its down-regulatory effects on CD64 , CD32, and CD16 expression were prevented by IL-10
Lehmann et al., J Immunol 1994 : In mouse peritoneal macrophages, IL-4 and IL-10 influenced both basal and IFN-gamma induced expression of Fc gamma RI in opposite ways : IL-10 was stimulatory and IL-4 repressed Fc gamma RI expression
Fanger et al., J Immunol 1997 : Both DC and monocyte CD64 expression was increased by IFN-gamma and IL-10 , but while monocyte CD64 was decreased by IL-4, DC CD64 remained unchanged
Bovolenta et al., J Immunol 1998 : Taken together, our data suggest that IL-10 is unable to induce FcgammaRI gene expression in neutrophils because the intracellular signaling pathway triggered by the cytokine is impaired at the level of, or upstream of, STAT1 and/or STAT3 activation