Gene interactions and pathways from curated databases and text-mining

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EGF — MAP2K6

Text-mined interactions from Literome

Kato-Stankiewicz et al., Proc Natl Acad Sci U S A 2002 (MAP Kinase Signaling System) : They also inhibited Ras induced Raf-1 activation in human embryonic kidney 293 cells, Raf-1 and mitogen activated protein kinase kinase 1 activities in HT1080 fibrosarcoma cells, and epidermal growth factor induced Raf-1 activation in A549 lung carcinoma cells
Moriguchi et al., Eur J Biochem 1995 : Activation of two isoforms of mitogen activated protein kinase kinase in response to epidermal growth factor and nerve growth factor
Stein et al., J Biol Chem 1996 : MEK6 is strongly activated by UV, anisomycin, and osmotic shock but not by phorbol esters, nerve growth factor, and epidermal growth factor