◀ Back to EGF
EGF — TGM3
Text-mined interactions from Literome
Caccamo et al., Life Sci 2004
(Carcinoma, Squamous Cell) :
In this work, we tested the
effects of all-trans retinoic acid and
EGF , used alone or in combination, on
transglutaminase activity in a squamous, epithelial carcinoma cell line, HEp-2 ... We demonstrated that nanomolar
EGF further
enhances transglutaminase activity previously induced by all-trans retinoic acid
Obinata et al., Dev Biol 1987
:
Furthermore,
EGF caused a twofold increase in glucocorticoid induced epidermal
transglutaminase activity and in the amount of epidermal glucocorticoid receptor ... In the absence of FCS, however,
EGF did not inhibit steroid induced alpha-type keratinization and did not
affect either steroid induced epidermal
transglutaminase activity or amount of epidermal glucocorticoid receptor ... Hence, the
effect of
EGF on glucocorticoid induced epidermal
transglutaminase activity was observed only in the presence of delipidized FCS and might be supported by an increase in the amount of glucocorticoid receptor
Dadabay et al., Biochemistry 1987
:
The increase in
transglutaminase activity could be
detected as early as 2 min after the addition of
EGF , with the maximal response attained by 30 min ... The demonstration that
EGF acutely
increases the activity of a soluble, intracellular
transglutaminase defines a novel pathway of growth factor action and provides a useful model system for identifying and comparing the mechanism ( s ) by which growth factors activate soluble enzymes
Sako et al., Cancer Res 1988
:
In mouse primary epidermal cells, on the other hand, staurosporine failed to block the effects of phorbol 12,13-dibutyrate on
epidermal growth factor binding and on
induction of ornithine decarboxylase and epidermal
transglutaminase
Katoh et al., Arch Biochem Biophys 1993
:
Calcium pretreatment
induces the decrease in
epidermal growth factor binding through the activation of
transglutaminase in isolated liver membrane
Monzon et al., Endocrinology 1996
(Carcinoma, Squamous Cell) :
In contrast, membrane associated
transglutaminase enzyme activity, which predominantly represents type 1 ( keratinocyte ) transglutaminase, is markedly
inhibited by
EGF