Gene interactions and pathways from curated databases and text-mining

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EGF — TGM3

Text-mined interactions from Literome

Caccamo et al., Life Sci 2004 (Carcinoma, Squamous Cell) : In this work, we tested the effects of all-trans retinoic acid and EGF , used alone or in combination, on transglutaminase activity in a squamous, epithelial carcinoma cell line, HEp-2 ... We demonstrated that nanomolar EGF further enhances transglutaminase activity previously induced by all-trans retinoic acid
Obinata et al., Dev Biol 1987 : Furthermore, EGF caused a twofold increase in glucocorticoid induced epidermal transglutaminase activity and in the amount of epidermal glucocorticoid receptor ... In the absence of FCS, however, EGF did not inhibit steroid induced alpha-type keratinization and did not affect either steroid induced epidermal transglutaminase activity or amount of epidermal glucocorticoid receptor ... Hence, the effect of EGF on glucocorticoid induced epidermal transglutaminase activity was observed only in the presence of delipidized FCS and might be supported by an increase in the amount of glucocorticoid receptor
Dadabay et al., Biochemistry 1987 : The increase in transglutaminase activity could be detected as early as 2 min after the addition of EGF , with the maximal response attained by 30 min ... The demonstration that EGF acutely increases the activity of a soluble, intracellular transglutaminase defines a novel pathway of growth factor action and provides a useful model system for identifying and comparing the mechanism ( s ) by which growth factors activate soluble enzymes
Sako et al., Cancer Res 1988 : In mouse primary epidermal cells, on the other hand, staurosporine failed to block the effects of phorbol 12,13-dibutyrate on epidermal growth factor binding and on induction of ornithine decarboxylase and epidermal transglutaminase
Katoh et al., Arch Biochem Biophys 1993 : Calcium pretreatment induces the decrease in epidermal growth factor binding through the activation of transglutaminase in isolated liver membrane
Monzon et al., Endocrinology 1996 (Carcinoma, Squamous Cell) : In contrast, membrane associated transglutaminase enzyme activity, which predominantly represents type 1 ( keratinocyte ) transglutaminase, is markedly inhibited by EGF