Gene interactions and pathways from curated databases and text-mining

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IL2 — ITIH4

Text-mined interactions from Literome

Robey et al., AIDS Res Hum Retroviruses 2001 (HIV Seropositivity) : Anti-cyclic C4 antibodies magnified gp120 induced suppression of IL-2 produced by T cells in vitro
Taoufik et al., Blood 1997 : Human immunodeficiency virus gp120 inhibits interleukin-12 secretion by human monocytes : an indirect interleukin-10 mediated effect
Kaneko et al., Clin Exp Immunol 1997 (HIV Infections) : We found that early T cell activation, as indicated by HLA-DP expression in the early G1 ( G1A ) phase of the cell cycle, and the inhibition of mitogen mediated IL-2 production induced by gp120 , required TNF-alpha produced by gp120 stimulated macrophages
Capobianchi et al., J Biol Regul Homeost Agents 1996 (Acquired Immunodeficiency Syndrome) : However, neither IL-4 ( Th2-type ) nor IL-2 ( Th1-type ), nor DNA synthesis are activated by gp120