Gene interactions and pathways from curated databases and text-mining

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AGTR2 — MMP2

Text-mined interactions from Literome

Brassard et al., Hypertension 2005 : Concomitant AT1/AT2 blockade prevented growth, reduced collagen type I and elastin deposition but increased vascular stiffness, fibronectin, and MMP-2 activity
Jing et al., Int J Mol Med 2009 : We conclude that Ang II enhances the MMP-2 expression via AT1R, and that enforces AT2R inhibited the same
Kunugi et al., Lab Invest 2011 (Necrosis...) : In MMP-2 ( +/+ ) mice, MMP-2 and MMP-9 activities increased significantly at 2 to 24?h, peaked at 6?h, after reperfusion
Chae et al., Environ Toxicol Pharmacol 2012 : The inhibitory effect of AAPE at 2µg/ml on MMP-2 activity was increased in the presence of phorbol myristate acetate ( PMA )