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IL13 — IL25

Text-mined interactions from Literome

Fort et al., Immunity 2001 (Eosinophilia...) : IL-25 induces IL-4, IL-5, and IL-13 and Th2 associated pathologies in vivo
Melk et al., Transplantation 2004 (Growth Disorders...) : During rhGH therapy in children with transplants, interleukin (IL)-2 production increased threefold at 4 weeks, and IL-4 and IL-13 increased by 70 % at 12 weeks
Kang et al., Am J Respir Cell Mol Biol 2005 (Pneumonia) : The production of interleukin (IL)-4 and IL-13 by activated T cells is involved in the augmentation of Th2-type immune responses to particles, and IL-25 induces the synthesis of IL-4 and IL-13
Maezawa et al., J Immunol 2006 (MAP Kinase Signaling System) : IL-25 ( IL-17E ) induces IL-4, IL-5, and IL-13 production from an unidentified non-T/non-B cell population and subsequently induces Th2-type immune responses such as IgE production and eosinophilic airway inflammation
Tamachi et al., Int Arch Allergy Immunol 2006 (Asthma...) : Interestingly, when systemically administered to mice, IL-25 induces IL-4, IL-5 and IL-13 production from undefined non-T/non-B cells and then induces Th2-type immune responses such as blood eosinophilia and increased serum immunoglobulin E levels
Kleinschek et al., J Exp Med 2007 (Encephalomyelitis, Autoimmune, Experimental...) : IL-25 treatment induced elevated production of IL-13 , which is required for suppression of Th17 responses by direct inhibition of IL-23, IL-1beta, and IL-6 expression in activated dendritic cells
Fichtner-Feigl et al., J Immunol 2007 (Colitis...) : In vitro stimulation studies suggest that this IL-13 production is dependent on IL-23 and IL-25 , but not on IL-12p70
Rickel et al., J Immunol 2008 : Unlike wild-type mice, cultured splenocytes from either IL-17RB KO or IL-17RA KO mice did not produce IL-5 or IL-13 in response to IL-25 stimulation, and both IL-17RB KO and IL-17RA KO mice did not respond to intranasal administration of IL-25
Terashima et al., J Exp Med 2008 (Asthma...) : IL-17RB ( + ) CD4 ( + ) NKT cells produce predominantly IL-13 and Th2 chemokines upon stimulation with IL-25 in vitro
Haber et al., Exp Parasitol 2009 (Hyperalgesia...) : Leishmania major : interleukin-13 increases the infection induced hyperalgesia and the levels of interleukin-1beta and interleukin-12 in rats
Swaidani et al., J Immunol 2009 (Eosinophilia...) : Although Act1-deficient mice showed reduced expression of KC ( CXCL1 ) and neutrophil recruitment to the airway compared with wild-type mice in response to IL-17 stimulation, Act1 deficiency abolished IL-25 induced expression of IL-4, IL-5, IL-13 , eotaxin-1 ( CCL11 ), and pulmonary eosinophilia
Caruso et al., Gastroenterology 2009 (Colitis, Ulcerative...) : IL-25 induced IL-13 production in the colon, but IL-13 was not required for suppression of PGN colitis
Cao et al., J Am Soc Nephrol 2011 (Acute Kidney Injury...) : IL-25 increased the levels of IL-4 and IL-13 in serum, kidney, renal draining lymph nodes, and CD4+ lymphocytes
Yang et al., PloS one 2013 : Macrophages produced type 2 cytokines IL-5 and IL-13 in response to the stimulation of IL-25/IL-33 in vitro, or were the IL-13 producing cells in mice administrated with exogenous IL-33 or infected with Heligmosomoides bakeri
Licona-Limón et al., Nat Immunol 2013 (Hypersensitivity) : Such studies have led to the identification of a new innate lymphoid subset that produces the canonical type 2 cytokines IL-5, IL-9 and IL-13 in response to IL-25 and IL-33