Gene interactions and pathways from curated databases and text-mining

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IL13 — TEC

Text-mined interactions from Literome

Zemans et al., Cell Immunol 2009 : Furthermore, LPS induced actin polymerization as well as MCP-1, tumor necrosis factor-alpha, interleukin-6 , and interleukin-1beta expression are dependent on Tec kinase activity
Schmidt et al., Eur J Immunol 2009 : Finally, a comparison of WT, Tec ( - ) ( / ) ( - ), Btk ( - ) ( / ) ( - ) and Tec ( - ) ( / ) ( - ) Btk ( - ) ( / ) ( - ) BMMC revealed a negative role for Btk in the regulation of IL-4 production, while for the efficient production of TNF-alpha, IL-13 and GM-CSF, both Tec and Btk were required