Yasuda et al., Lab Invest 2003
(Arthritis, Rheumatoid) :
Integrin alpha4beta1 may be partially involved in the MMP induction by COOH-HBFN-f
Huhtala et al., J Cell Biol 1995
:
In contrast, peptide V from the heparin binding region, shown previously to stimulate focal contact formation, further enhanced MMP expression by RSF when present on the substrate with 120FN. RSF expressed alpha 4 beta 1 integrin , the receptor for CS-1, and the anti-alpha 4 mAb blocked the ability of CS-1 to suppress MMP induction by 120FN
Madri et al., Biochem Cell Biol 1996
(Inflammation) :
We have demonstrated that matrix metalloxproteinase-2 (MMP-2) is induced in T cells upon adhesion to endothelial cells and that the induction of MMP-2 is mediated by binding of T cell VLA-4 to VCAM-1