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IL11 — TIMP1
Text-mined interactions from Literome
Alexander et al., Curr Eye Res 1998
:
A phorbol mitogen ( TPA ), and TNF alpha and beta,
interleukin-1 alpha and PDGF BB
stimulate gelatinase B, stromelysin, interstitial collagenase and
TIMP-1 expression, while having negligible effects on gelatinase A expression ; TIMP-2 levels are reduced by TNF but not affected by the other treatments
Hermann et al., Arthritis Rheum 1998
(Arthritis, Rheumatoid) :
However, exogenous
IL-11 directly inhibited spontaneous MMP-1 and MMP-3 production, and
up-regulated TIMP-1 in RA synovial tissue