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IL21 — REL

Text-mined interactions from Literome

Grumont et al., J Exp Med 2001 : c-Rel regulates interleukin 12 p70 expression in CD8 ( + ) dendritic cells by specifically inducing p35 gene transcription
Temmerman et al., Blood 2006 (Ectodermal Dysplasia...) : As a consequence, CD40 stimulated EDI DCs failed to synthesize the c-Rel dependent cytokine interleukin-12 , had impaired up-regulation of costimulatory molecules, and failed to support allogeneic lymphocyte proliferation in vitro
Chen et al., J Immunol 2010 (Encephalomyelitis, Autoimmune, Experimental) : In this study, we demonstrate that c-Rel , a member of the NF-kappaB family of transcription factors, is required for IL-21 gene expression in T lymphocytes ... Taken together, c-Rel plays an important role in the expression of IL-21 in T cells and subsequently in IL-21 dependent T ( FH ) cell development