Gene interactions and pathways from curated databases and text-mining

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BAX — VDAC2

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Shimizu et al., Proc Natl Acad Sci U S A 2000 (Ion Channel Gating) : Furthermore, BH4 oligopeptides of Bcl-2 and Bcl-x ( L ), but not mutant peptides, were able to inhibit both VDAC activity on liposomes even in the presence of Bax and apoptotic Deltapsi loss in isolated mitochondria
Shimizu et al., J Cell Biol 2001 : Furthermore, we used these antibodies to show that Bax- and Bak induced lysis of red blood cells was also mediated by the VDAC on plasma membrane
Roucou et al., Biochem J 2002 : The presence of the voltage dependent anion channel was not required either for Bax oligomerization or for Bax induced cytochrome c release
Ozaki et al., Biochim Biophys Acta 2009 : This cleavage of VDAC promotes the mitochondrial accumulation of Bax and the release of tAIF from mitochondria