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CCNA2 — JUN
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
-
STRING interaction:
CCNA2
—
JUN
(interaction, mapped from kegg_pathways)
-
STRING interaction:
JUN
—
CCNA2
(interaction, mapped from grid bind)
Text-mined interactions from Literome
Katabami et al., J Biol Chem 2005
:
Using a dominant negative c-Jun mutant, TAM67, we showed that this transcriptional activation of
cyclin A2 requires
c-Jun
Quan et al., J Invest Dermatol 2010
:
Ultraviolet irradiation
induces CYR61/CCN1 , a mediator of collagen homeostasis, through activation of transcription factor
AP-1 in human skin fibroblasts
Dash et al., Oncogene 2010
(Cell Transformation, Neoplastic...) :
Overall, SARI can directly inhibit CCN1 induced transformation by inhibiting the transcription of
CCN1 , as well as indirectly by
inhibiting the expression of
c-Jun ( and hence blocking AP-1 activity )