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JUN — MAPK8IP1
Text-mined interactions from Literome
Bonny et al., J Biol Chem 2000
:
Reducing
IB1 levels in these cells
increased phosphorylation of
c-Jun and increased the apoptotic rate in presence of IL-1beta
Fan et al., J Biol Chem 2000
(MAP Kinase Signaling System) :
Stable expression of the JNK scaffold protein
JIP-1 blocked vinblastine induced phosphorylation of
c-Jun and ATF-2, but did not affect Bcl-2/Bcl-X ( L ) phosphorylation, confirming a bifurcation in JNK signaling involving both nuclear and non-nuclear substrates
Ikezoe et al., Br J Cancer 2004
(Prostatic Neoplasms) :
Thus, TPA stimulated
c-Jun through JNK, and
JIP-1 effectively
blocked JNK
Morel et al., Mol Cell Biol 2010
(Fatty Liver...) :
Requirement of
JIP1 mediated
c-Jun N-terminal kinase activation for obesity induced insulin resistance
Mooser et al., Genomics 1999
:
Islet-brain 1 (IB1), a regulator of the pancreatic beta-cell function in the rat, is homologous to
JIP-1 , a murine
inhibitor of
c-Jun amino-terminal kinase (JNK)