Schuringa et al., Biochem J 2000
(Carcinoma, Hepatocellular...) :
Interleukin-6 induced STAT3 transactivation and Ser727 phosphorylation involves Vav , Rac-1 and the kinase SEK-1/MKK-4 as signal transduction components
Faruqi et al., Proc Natl Acad Sci U S A 2001
:
The expression of Vav ( Delta1-187 ), a constitutively active guanine nucleotide exchange factor for the Rho GTPases, or activated forms of Ras or Rho family members, leads to STAT3-specific activation