Gene interactions and pathways from curated databases and text-mining

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HBEGF — PDX1

Text-mined interactions from Literome

Campbell et al., Biochem Biophys Res Commun 2002 : The current study has established the fact that glucose, GLP-1, insulin, T ( 3 ), HB-EGF , and TNF-alpha all positively regulate the PDX1 gene promoter in pancreatic beta-cells
Kaneto et al., J Biol Chem 1997 : Based on findings that the expression pattern was similar to that of the homeodomain containing transcription factor PDX-1 ( IDX-1/STF-1/IPF1 ) and that the regulatory region of the HB-EGF gene contained sequences similar to the PDX-1 binding A element, we examined whether PDX-1 could be a potential activator of HB-EGF gene expression