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CDK2 — HSP90AA1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: CDK2 — HSP90AA1 (physical association, affinity chromatography technology) Neganova et al., Stem Cells 2011
• IRef Biogrid Interaction: CDK2 — HSP90AA1 (physical association, affinity chromatography technology) Varjosalo et al., Nat Methods 2013
• IRef Intact Interaction: Complex of 30 proteins (association, tandem affinity purification) Varjosalo et al., Nat Methods 2013

Text-mined interactions from Literome

Muñoz et al., Genetics 1999 : Hsp90 complexes are required for CDK regulation ; the synergy found between the excess of Wos2 and a deficiency in Hsp90 activity suggests that Wos2 could specifically interfere with the Hsp90 dependent regulation of Cdc2
Bourke et al., Oncogene 2010 : Cdk2 controls normal centrosome duplication, but Chk1 dependent centrosome amplification also occurs after DNA damage
Halder et al., FEBS J 2012 : Inhibition of upstream Hsp90 by TF and TR consequently attenuated Akt signaling and reduced the level of CDK2