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HSP90AA1 — JUN
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Tago et al., Life Sci 2004
:
Hsp90 inhibitors
attenuate effect of dexamethasone on activated NF-kappaB and
AP-1 ... These results suggest that
Hsp90 inhibitor itself
inhibits the activation of NF-kappaB and
AP-1 , however, impedes Dex induced inhibition of IL-1beta induction by attenuating Dex mediated activation of GR and inhibition of the proinflammatory transcription factors
Murata et al., Int J Mol Med 2005
(Arthritis, Rheumatoid...) :
The findings indicate that
HSP90 is required for increased AP-1 binding activity of rheumatoid synovial cells under inflammatory stimuli and that
AP-1 binding activity is
inhibited by functionally inactivating HSP90 with the inhibitors