Gene interactions and pathways from curated databases and text-mining

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IRF6 — NR4A1

Text-mined interactions from Literome

Pei et al., J Biol Chem 2005 (Arteriosclerosis...) : Mutation of these elements inhibited LPS dependent expression of the Nur77 promoter in transient transfection assays ... Furthermore, induction of Nur77 expression by LPS was severely compromised in fibroblasts lacking the three NF-kappaB subunits, Nfkb1, c-Rel, and RelA
Pang et al., Biochim Biophys Acta 2012 (Inflammation) : Minocycline inhibited LPS induced activation of the lectin-like oxidized low density lipoprotein receptor-1 ( LOX-1 ), NF-?B, LPS induced TNF-a factor ( LITAF ) and the Nur77 nuclear receptor