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IL17A — IL1B

Text-mined interactions from Literome

Van bezooijen et al., J Bone Miner Res 1999 (Bone Resorption) : In addition, IL-17 increased TNF-alpha induced IL-1alpha, IL-1beta , and IL-6 mRNA expression in fetal mouse metatarsals and IL-1alpha and IL-6 mRNA expression in MC3T3-E1 cells
Li et al., Proc Natl Acad Sci U S A 2000 : In a survey of cytokine induction, IL-17B and IL-17C stimulate the release of tumor necrosis factor alpha and IL-1beta from the monocytic cell line, THP-1, whereas IL-17 has only a weak effect in this system
Trajkovic et al., J Neuroimmunol 2001 (Astrocytoma) : While IL-17 stimulated both IL-1beta and IL-6 production in astrocytes, only IL-1 was partly responsible for IL-17 induced NO release
Ye et al., Am J Respir Cell Mol Biol 2001 (Klebsiella Infections...) : Moreover, overexpression of IL-17 in the pulmonary compartment using a recombinant adenovirus encoding murine IL-17 ( AdIL-17 ) resulted in the local induction of tumor necrosis factor-alpha, IL-1beta , macrophage inflammatory protein-2, and granulocyte colony stimulating factor ( G-CSF ) ; augmented polymorphonuclear leukocyte recruitment ; and enhanced bacterial clearance and survival after challenge with K. pneumoniae
Shimada et al., J Immunol 2002 : Furthermore, IL-17, IL-1beta , and TNF-alpha induced a rapid activation of extracellular signal related kinase p42/44 and p38 MAPKs, and specific MAPK inhibitors ( SB203580, PD98059, and U0216 ) significantly reduced IL-17- , IL-1beta-, or TNF-alpha induced IL-6 secretion, indicating the role of MAPKs in the induction of IL-6
Benderdour et al., J Rheumatol 2002 (Osteoarthritis) : Interleukin 17 (IL-17) induces collagenase-3 production in human osteoarthritic chondrocytes via AP-1 dependent activation : differential activation of AP-1 members by IL-17 and IL-1beta
Honorati et al., Osteoarthritis Cartilage 2002 (Osteoarthritis) : IL-17 and TNF-alpha stimulated IL-1beta release in few subjects
Dulos et al., Arthritis Rheum 2005 (Arthritis, Rheumatoid) : Exposure to the proinflammatory cytokines TNFalpha, IL-1alpha, IL-1beta , and IL-17 increases CYP7B activity in synovial tissue
Sutton et al., J Exp Med 2006 (Encephalomyelitis, Autoimmune, Experimental) : IL-23 alone did not induce IL-17 production by T cells from IL-1RI ( -/- ) mice, and IL-23 induced IL-17 production was substantially enhanced by IL-1alpha or IL-1beta , even in the absence of T cell receptor stimulation
Dragon et al., Am J Physiol Lung Cell Mol Physiol 2007 : Erk1/2 and p38 modulated IL-17 and IL-1beta CXCL-8 promoter activity ; however, IL-1beta also activated the PI3K pathway
Beklen et al., J Dent Res 2007 (Periodontitis) : IL-17 was less potent as a direct MMP inducer than IL-1beta and TNF-alpha, but it induced IL-1beta and TNF-alpha production from macrophages, and IL-6 and IL-8 from gingival fibroblasts
Kim et al., Immunol Lett 2007 (Arthritis, Rheumatoid...) : TLR stimulation of RA-FLS also induced the production of IL-1beta and TNF-alpha to a lesser extent ; however, it had no effect on IL-17 production
Cheung et al., J Immunol 2008 (Inflammation) : IL-17A, IL-17F , and IL-23 could induce the release of chemokines GRO-alpha/CXCL1, IL-8/CXCL8, and MIP-1beta/CCL4 from eosinophils, while IL-17F and IL-23 could also increase the production of proinflammatory cytokines IL-1beta and IL-6
Manel et al., Nat Immunol 2008 : We show here that TGF-beta, IL-1beta and IL-6, IL-21 or IL-23 in serum-free conditions were necessary and sufficient to induce IL-17 expression in naive human CD4+ T cells from cord blood
Yang et al., Nature 2008 : Here we confirm that whereas IL-1beta and IL-6 induce IL-17A secretion from human central memory CD4 ( + ) T cells, TGF-beta and IL-21 uniquely promote the differentiation of human naive CD4 ( + ) T cells into T ( H ) 17 cells accompanied by expression of the transcription factor RORC2
Kattah et al., Arthritis Rheum 2008 : IL-1beta and IL-6 independently induced IL-21 secretion, but the presence of IL-21 alone was not sufficient for IL-17 production
Liu et al., J Immunol 2008 : IL-1beta alone or in association with IL-23 and IL-6 markedly increase IL-17 ( + ) CCR6 ( + ) memory T cells and induce IL-17 production in CCR6 ( - ) memory T cells
Hashizume et al., Rheumatology (Oxford) 2008 (Arthritis, Rheumatoid) : On the other hand, TNF-alpha and IL-17 did not induce RANKL expression, although TNF-alpha, IL-17 or IL-1beta stimulated cell growth and IL-6 production
Mills et al., Eur J Immunol 2008 (Immune System Diseases...) : Furthermore, IL-1alpha or IL-1beta in synergy with IL-23 can promote IL-17 secretion from memory T cells
Eyerich et al., J Allergy Clin Immunol 2009 (Dermatitis, Atopic...) : IL-17 secretion was not enhanced by IL-23, IL-1 beta , or IL-6 but was enhanced by the S aureus derived superantigen staphylococcal enterotoxin B
Lyakh et al., Immunol Rev 2008 : IL-23, IL-6, transforming growth factor ( TGF-beta1 ), and IL-1beta in supernatants from activated human DCs induce human naive CD4 ( + ) T cells to produce IL-17
McCandless et al., J Immunol 2009 (Encephalomyelitis, Autoimmune, Experimental) : In addition, gammadelta T cells are also targets of this cytokine, contributing to IL-1beta mediated production of IL-17
Harada et al., Clin Exp Immunol 2009 (Autoimmune Diseases...) : Moreover, BECs possessed IL-17-receptors and stimulation with IL-17 induced production of IL-6, IL-1 beta , IL-23p19 and chemokines
Ito et al., Arthritis Rheum 2009 (Arthritis, Experimental...) : Furthermore, IL-17 production by gamma/delta T cells was induced by IL-1beta plus IL-23 independently of T cell receptor
Guo et al., Proc Natl Acad Sci U S A 2009 : Similarly, Th17 cells produce IL-17A in response to IL-1beta and a STAT3 activator and Th1 cells produce IFNgamma in response to IL-18 and a STAT4 inducer
Sutton et al., Immunity 2009 (Encephalomyelitis, Autoimmune, Experimental) : Here, we show that gammadelta T cells express IL-23R and the transcription factor RORgammat and produce IL-17 , IL-21, and IL-22 in response to IL-1beta and IL-23, without T cell receptor engagement
Rovedatti et al., Gut 2009 (Colitis, Ulcerative...) : IL23 and IL1beta plus IL6 had no effect on IBD LPMC production of IL17 ; however, IL12 markedly increased IFNgamma production and decreased IL17 production
Hillyer et al., Rheumatology (Oxford) 2009 (Arthritis, Rheumatoid) : IL-17A protein was detected in approximately 40 % of the supernatants and IL-17A blockade, in IL-17A producing cultures, resulted in a small but significant inhibition of TNF-alpha ( 38 % ), IL-1beta ( 23 % ) and IL-6 ( 22 % )
Baldeviano et al., Circ Res 2010 (Cardiomyopathies...) : Flow cytometric and cytokine analysis revealed an important role for IL-17A in heart-specific upregulation of IL-6, TNFalpha, and IL-1beta and the recruitment of CD11b ( + ) monocyte and Gr1 ( + ) granulocyte populations into the heart
Datta et al., Proc Natl Acad Sci U S A 2010 : Furthermore, IL-17 is involved in the induction of serum and mucosal antibody responses by CT. Th17 cells induced by CT have a unique cytokine profile compared with those induced by IL-6 and TGF-beta, and their induction by CT requires cAMP dependent secretion of IL-1beta and beta-calcitonin gene related peptide by dendritic cells
Cella et al., Proc Natl Acad Sci U S A 2010 : IL-1beta promoted constitutive IL-22 secretion rather than acute IL-22 production in response to IL-23 and induced IL-17 in some cells