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MMP12 — MMP8

Text-mined interactions from Literome

Holopainen et al., Invest Ophthalmol Vis Sci 2003 : Activation of matrix metalloproteinase-8 by membrane type 1-MMP and their expression in human tears after photorefractive keratectomy
Tan et al., Am J Respir Cell Mol Biol 2006 (Pneumonia...) : No increases in RNA levels of MMP-2, MMP-9 , or MMP-8 were found, but levels of MMP-7, MMP-12 , and MMP-13 RNA did increase at 14 d
Barbour et al., J Thorac Cardiovasc Surg 2006 (Aortic Aneurysm, Thoracic) : Active matrix metalloproteinase 8 ( collagenase ) levels increased at 72 hours ( 178 % +/- 49 %, P < .05 from control ), and active matrix metalloproteinase 12 ( elastase ) levels increased by 24 hours ( 138 % +/- 11 %, P < .05 ), whereas active matrix metalloproteinase 2 levels increased at 72 hours and 1 week after thoracic aortic aneurysm induction ( 72 hours : 158 % +/- 12 %, 1 week : 162 % +/- 19 % ; P < .05 )
Madala et al., J Immunol 2010 (Fibrosis...) : Instead, we observed marked increases in MMP2 and MMP13 expression, suggesting that Mmp12 was promoting fibrosis by limiting the expression of specific ECM degrading MMPs. Interestingly, like MMP12 , MMP13 expression was highly dependent on IL-13 and type II-IL-4 receptor signaling
Li et al., PloS one 2012 (Disease Models, Animal...) : Similar results were observed in the study using MMP408 , a pharmacological inhibitor of MMP-12