Gene interactions and pathways from curated databases and text-mining

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IL21 — KLRD1

Text-mined interactions from Literome

Eberl et al., Cell Immunol 2002 : HMB-PP stimulated Vgamma9/Vdelta2 T cells proliferated, expressed CCL5/RANTES, and upregulated markers like CD16, CD25, CD69, and CD94 , in the presence of either IL-15 or IL-21
Ebert et al., Immunology 2009 : IL-21 had no effect on Fas ligand (FL)- or tumour necrosis factor-alpha (TNF-alpha) mediated cytotoxicity, but it down-regulated IL-15 stimulated expression of CD25 and CD94 , indicating that it has both positive and negative actions