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JUN — PML

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: PML — JUN (colocalization, imaging technique) Yasuda et al., Genes Cells 1999*
• IRef Biogrid Interaction: PML — JUN (physical association, affinity chromatography technology) Salomoni et al., Blood 2005*
• IRef Biogrid Interaction: PML — JUN (physical association, affinity chromatography technology) Seo et al., Mol Cell 2006*
• IRef Biogrid Interaction: PML — JUN (direct interaction, pull down) Seo et al., Mol Cell 2006*
• IRef Biogrid Interaction: PML — JUN (direct interaction, pull down) Vallian et al., Oncogene 1998*
• IRef Hprd Interaction: Complex of 17 proteins (in vivo) Vallian et al., Oncogene 1998*

Text-mined interactions from Literome

Salomoni et al., Blood 2005 : We demonstrate that c-Jun is required for UV-induced apoptosis and that PML is essential for both c-Jun transcriptional activation and DNA binding upon UV radiation
Cheng et al., J Biol Chem 2005 : However, the ability of SuPr-1 to enhance c-Jun transcription is dependent on promyelocytic leukemia but is independent of the desumoylation activity of SuPr-1
Santiago et al., Cell cycle (Georgetown, Tex.) 2009 : PML also activates c-Jun , which requires all three sumoylation sites
Vallian et al., Oncogene 1998 : There is significant sequence homology between the dimerization domain of PML and the Fos family of proteins, which imply that PML may be involved in AP-1 activity