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INS — MDM2

Text-mined interactions from Literome

Usui et al., Mol Cell Biol 2004 : Insulin stimulated the association of IRS-1 and Mdm2 , an E3 ubiquitin ligase, and this association was inhibited to overexpression of WT beta-arrestin-1, which led by decreased ubiquitin content of IRS-1, suggesting that both beta-arrestin-1 and IRS-1 competitively bind to Mdm2
Ohsaka et al., Cryobiology 2010 : Insulin-like growth factor-I and insulin induce the production of phospho-Ser-166 MDM2 , a target of Akt, and influence the formation of the MDM2 complex