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CDKN2A — CTBP1
Text-mined interactions from Literome
Skalska et al., PLoS Pathog 2010
(Epstein-Barr Virus Infections) :
Epigenetic repression of
p16(INK4A) by latent Epstein-Barr virus
requires the interaction of EBNA3A and EBNA3C with
CtBP ... These novel LCLs have revealed that the chromatin remodelling and epigenetic repression of
p16(INK4A) requires the interaction of both EBNA3A and EBNA3C with
CtBP
Deng et al., J Invest Dermatol 2013
(Disease Progression...) :
Our findings suggest an important
role of
CtBP1 in the transcriptional control of
p16INK4a and Brca1, with CtBP1 overexpression potentially contributing to increased proliferation and DNA damage in melanoma