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IL15RA — RELA
Text-mined interactions from Literome
Pereno et al., Oncogene 2000
(Melanoma) :
Thus,
IL-15Ralpha controls
NF-kappaB activation, however differences in the intracellular trafficking of the IL-15 and/or IL-15Ralpha suggest a different biological role for this complex in MELP versus MELREO cells
Mariner et al., J Immunol 2001
(Leukemia-Lymphoma, Adult T-Cell) :
Furthermore, using promoter deletion constructs and gel shift analysis, we defined a functional NF-kappaB binding motif in the human IL-15Ralpha promoter, suggesting that Tax activation of
IL-15Ralpha is
due , in part, to the induction of
NF-kappaB
Mariner et al., J Immunol 2002
:
These findings suggest a
role for both
NF-kappaB and IRF-4 in the transcriptional regulation of
IL-15Ralpha by HTLV-I Tax