Sakaguchi et al., Biochem Biophys Res Commun 2001
:
These results suggest that EGF stimulates Shc-AP2 complex formation and association of Shc-AP2 complexes with EGF receptors
Yun et al., J Biol Chem 2008
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The interaction of PLC-epsilon with AP2 was responsible for the suppression of EGF receptor down-regulation, since a perturbation in this interaction abolished this effect