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ILK — ITGB1
Pathways - manually collected, often from reviews:
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
-
IRef Bind Interaction:
ITGB1
—
ILK
Hannigan et al., Nature 1996*
-
IRef Bind_translation Interaction:
ITGB1
—
ILK
(coimmunoprecipitation)
Hannigan et al., Nature 1996*
-
IRef Bind_translation Interaction:
ITGB1
—
ILK
(two hybrid)
Hannigan et al., Nature 1996*
-
IRef Biogrid Interaction:
ILK
—
ITGB1
(physical association, affinity chromatography technology)
Hannigan et al., Nature 1996*
-
IRef Hprd Interaction:
ILK
—
ITGB1
(in vitro)
Hannigan et al., Nature 1996*, Delcommenne et al., Proc Natl Acad Sci U S A 1998
-
IRef Hprd Interaction:
ILK
—
ITGB1
(in vivo)
Hannigan et al., Nature 1996*, Delcommenne et al., Proc Natl Acad Sci U S A 1998
-
IRef Intact Interaction:
Complex of 400 proteins
(association, cross-linking study)
Humphries et al., Science signaling 2009
-
IRef Ophid Interaction:
ITGB1
—
ILK
(aggregation, interologs mapping)
Brown et al., Bioinformatics 2005
-
IRef Ophid Interaction:
ITGB1
—
ILK
(aggregation, confirmational text mining)
Delcommenne et al., Proc Natl Acad Sci U S A 1998
Text-mined interactions from Literome
Dogra et al., J Cell Physiol 2006
(Muscular Dystrophy, Animal) :
Finally, cellular levels of Bcl-2, cIAP1, and
integrin beta1 and
activation of
integrin linked kinase were higher in diaphragm muscle of mdx mice compared to normal mice
Camacho-Leal et al., J Cell Physiol 2007
(MAP Kinase Signaling System) :
Inhibition of PI3-K and
ILK , but not MAPK,
prevented the
alpha5beta1 integrin activation
Chen et al., Biochem Pharmacol 2008
:
Astragaloside IV improves high glucose induced podocyte adhesion dysfunction via
alpha3beta1 integrin upregulation and
integrin linked kinase inhibition ... These results suggest that AS-IV improve HG-induced podocyte adhesion dysfunction, which is partly attributed to
alpha(3)beta(1) integrin upregulation and
ILK inhibition